Summary of Product Characteristics: Benadryl Allergy Oral Solution/Benadryl Allergy Children's 1mg/ml oral solution. McNeil Products Ltd. Revised May 2010. Most antihistamines can be bought from pharmacies and shops, but some are only available on prescription. Types of antihistamine Double blind controlled clinical trials comparing cetirizine to placebo or other antihistamines at the recommended dosage (10 mg daily for cetirizine), of which quantified safety data are available, included more than 3200 subjects exposed to cetirizine. Always be sure to follow your doctor's instructions and read all information provided to avoid such symptoms. Do hay fever tablets work? It is not known if cetirizine crosses the human placenta to the foetus. The molecular weight (about 462 for the dihydrochloride salt) is low enough, however, that transfer to the foetus should be expected.

Children aged 12 and over can take cetirizine capsules, tablets and liquid that you buy from pharmacies and supermarkets.Paediatric population: The half-life of cetirizine was about 6 hours in children of 6-12 years and 5 hours in children 2-6 years. In infants and toddlers aged 6 to 24 months, it is reduced to 3.1 hours. There may be a risk the medicines do not mix, which could stop either from working properly or increase the risk of side effects. Urticaria is a condition where an itchy skin rash develops. The rash can be triggered by an allergy to a substance such as a soap or a detergent. It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

Trusted by thousands nationwide to battle hay fever symptoms every year, these tablets are strong and non-drowsy so they let you carry on with your days as close to normal as possible with just one tablet daily. FAQs: What are the types of hay fever tablets? Children aged 2 and over can take cetirizine liquid bought from pharmacies or prescribed by their doctor.

Toxicity

In a fertility and reproduction study in mice, cetirizine did not negatively impact fertility at an oral dose of 64 mg/kg (approximately 25 times the maximum recommended daily oral dose in adults) . when to take it – including how many times a day you can take it and when to take it (some types should be taken before bedtime) In paediatric patients suffering from renal impairment, the dose will have to be adjusted on an individual basis taking into account the renal clearance, age and body weight of the patient.

Response to allergy skin tests are inhibited by antihistamines and a wash-out period (of 3 days) is required before performing them. Loratadine is usually recommended if you need to take an antihistamine in pregnancy. Loratadine or cetirizine are usually OK to take while breastfeeding. If you no longer have the leaflet that came with your medicine, you can search for an online version of it using our medicines A to Z. You may wonder why you get hay fever. Hay fever happens when your immune system overreacts to things like pollen. Your immune system produces antibodies that bind to cells in your nose and eyes. When you encounter the allergen again, these cells release chemicals like histamine, causing symptoms such as sneezing, itching, and watery eyes. Hay fever symptoms are usually seasonal because they're triggered by specific allergens like tree or grass pollen.Always take cetirizine tablets or capsules with a drink of water, milk or juice. Swallow them whole. Do not chew them.

Some antihistamines may not be suitable in these cases. A pharmacist or doctor can recommend one that's best for you. Carcinogenesis and mutagenesis: In a 2-year carcinogenicity study in rats, cetirizine was not shown to be carcinogenic at dietary doses up to 20 mg/kg (approximately 15 times the maximum recommended daily oral dose in adults). In a 2-year carcinogenicity study in mice, cetirizine administration lead to an incidence of benign liver tumors in males at a dietary dose of 16 mg/kg (approximately 6 times the maximum recommended daily oral dose in adults). The clinical significance of these findings during long-term use of cetirizine is unknown at this time . Oral LD50 (rat): 365 mg/kg; Intraperitoneal LDLO (mouse): 138 mg/kg; Oral TDLO (rat): 50 mg/kg; Oral TDLO (mouse): 0.1 mg/kg .

Taking antihistamines with other medicines, food or alcohol

Hepatic impairment: Patients with chronic liver diseases (hepatocellular, cholestatic, and biliary cirrhosis) given 10 or 20 mg of cetirizine as a single dose had a 50 % increase in half-life along with a 40 % decrease in clearance compared to healthy subjects. are due to have an allergy test – taking cetirizine may affect the results, so you might need to stop taking it a few days before the test how to take it – including whether it needs to be taken with water or food, or how to use it correctly (if eyedrops or a nasal spray)