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A 2020 meta-analysis of studies found garlic supplements to reduce blood pressure in people with high blood pressure. Researchers linked this effect to a 16–40% reduced risk of experiencing cardiovascular events. However, throughout ancient history, people widely used garlic for its health and medicinal properties. There is documented evidence of its use by many major civilizations, including the Egyptians, Greeks, Romans, Chinese, and Indians. Scientists now know that most of garlic’s health benefits are due to the formation of sulfur compounds when you chop, crush, or chew a garlic clove. Ansary J, et al. (2020). Potential health benefit of garlic based on human intervention studies: A brief overview.
SAC decreases CCl 4-induced liver injury by attenuation of oxidative stress, and can be a useful regimen for chronic liver disease ( Reference Kodai, Takemura and Minamiyama 68 ). Freshly prepared garlic homogenate has been shown to protect against isoniazid+rifampicin-induced liver injury in an experimental animal model ( Reference Pal, Vaiphei and Sikander 69 ). In rat liver cultures, garlic administration before exposure to hepatotoxins (such as carbon tetrachloride, galactosamine and doxorubicin) provided protection against histological and biochemical evidence of damage ( Reference Fancelli, Castro and de Toranzo 70 ). Answer: This is not advisable. Experts suggest that it is best to take the capsules after meals for better digestion. L. Bayan et al., Avicenna Journal of Phytomedicine, "Garlic: a review of potential therapeutic effects."But despite the bulb part of the plant being known for its medicinal uses, the name itself seems to come from the shallot-like top part of the plant, which is typically quite tight and pointy. “Gar” is the Anglo-Saxon for spear, and “lac” is for plant. At present, there are no known toxic compounds in garlic and its extracts. Chronic administration of garlic powder (50 mg/d) resulted in inhibition of spermatogenesis in rats. Reduced concentration of sialic acid in the testes, epididymis and seminal vesicles together with decreased leydig cell function reflect anti-androgenic effects of garlic ( Reference Augusti and Mathew 113 ). A higher concentration of garlic powder (200 mg/ml) or allicin isolated from garlic caused considerable cell injuries in the portal hepatic zone in isolated perfused rat liver ( Reference Dixit and Joshi 114 ), which was not observed at a lower concentration.
Tell your doctor right away if any of these rare but very serious side effects occur: easy or unusual bruising/bleeding. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. It is believed that the builders of the Egyptian pyramids were plied with garlic to keep their strength up.
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Allicin can also help with nitric oxide release in the blood vessels, thereby relaxing them and helping to bring about a drop in blood pressure. That, long term, is good for supporting heart health. Qu Z, et al. (2016). Protective effects of AGE and its components on neuroinflammation and neurodegeneration. Song X, et al. (2021). Biological functions of diallyl disulfide, a garlic-derived natural organic sulfur compound.
Garlic is available as capsules. Some have been deodorised or have a coating to prevent giving your breath that tell-tale garlic odour. What does garlic do in the body? The whole bulbs are heated over several weeks, and the garlic ends up with a sweet and syrupy taste, with a hint of tang. It is also elastic and has a chewy texture.Ried K. Garlic lowers blood pressure in hypertensive individuals, regulates serum cholesterol, and stimulates immunity: an updated meta-analysis and review. J Nutr. 2016;146(2):389S-396S. doi:10.3945/jn.114.202192 Tesfaye A. (2021). Revealing the therapeutic uses of garlic (Allium sativum) and its potential for drug discovery. Tedeschi P, et al. (2022). Therapeutic potential of allicin and aged garlic extract in Alzheimer’s disease. Zarezadeh M, et al. (2017). Garlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms. Use of Natural Products by Children : What the Science Says. NCCIH. https://www.nccih.nih.gov/health/providers/digest/use-of-natural-products-by-children-science
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