Sixty-seven patients completed the study. After 2 months of treatment, the difference of mean change from the baseline was greater for MEBO (vs placebo) for WSA mean (SD) −6.0 (−8.8, −3.3), PUSH Tool −2.6 (−4.7, −1.5), and VAS score −2.9 (−4.4, −1.7). On the basis of the questionnaire, the pressure ulcers were “completely healed” (50.0% vs 16.7%) ( P< .05) in patients after 2 months of treatment with MEBO versus placebo. No major adverse effects were found in the 2 groups. Conclusion: Atiyeh BS, Dham R, Dib M: Cost-Effectiveness of Moist Exposed Burn Therapy. [ http://en.mebo.com/paper/PDFpaper/155%20Atiyeh%201%202004.pdf]

The look of a scar will typically fade with time, though some changes may last longer or be permanent. Scaraway Clear Silicone Scar Sheets contain medical grade silicone which the company claims to be the number one ingredient in reducing the formation and appearance of scars. Additionally, it claims that these sheets are recommended by dermatologists and plastic surgeons. No significant differences were observed (p > 0.05 in all cases) between groups and subgroups on the time spent per course of treatment by doctors and nurses. Incremental cost effectiveness Carayanni V: Constructing confidence intervals around incremental cost effectiveness ratios in health care evaluations: A review. Journal of Statistics and Μanagement Systems. 2007, 10 (4): 1304-1310. Total groups: MEBO presented lower total cost per patient (although not significantly different: p = 0.10). The mean cost per patient was nearly by 36.55 € lower in the MEBO group. Significant differences in favor of the MEBO group were observed in the case of the mean cost of medical visits per patient (€5.31 versus €5.96, p = 0.01), hospitalization costs (€463.5 versus €512.22, p = 0.02) and costs of analgesics (€0.09 versus €016, p = 0.00). On the contrary, the mean cost of inflammatory medicines consumed by the MEBO group was significantly different from 0 (p = 0.00) and the mean cost of local agents was significantly higher in the MEBO group (€20.96 versus €11.40, p = 0.00). All other differences in partial costs were not significant. We have to mention also that the MEBO group presented an observed costlier consumption of antibiotics (mean: 33.91 versus mean: 31.41) not proved, nevertheless statistically significant (p = 0.09).

According to large-sample statistics (over 350,000 patients per annum), the total curative rate of MEBO burn repair is 99.42% Patients were excluded as follows: undertaking other therapies that could affect healing, such as corticosteroids, radiation therapy, or chemotherapy for cancer; complications of peripheral vascular disease, malignant tumors, diabetes mellitus, or infection; and severe diseases, including liver, cardiac, and kidney diseases, and serious relevant complications. 2.4 Randomization and allocation concealment Statistical tests of homogeneity for the different patient characteristics (e.g. gender, age, type of burns, skin photo type, burn surface area, TEWL at the 1rst day, toxic habits, co-morbidity etc), as well as for intermediate outcomes were used (χ 2 test variables t-test and Mann Whitney test for non normal data). All analyses were made according to the intention to treat principle. Incremental Cost Effectiveness Ratio Additionally, people may wish to look at the ingredients and see which are better suited to their skin type. A person with sensitive skin may for example wish to avoid harsh chemicals that may irritate their skin.

Allantoin is a naturally occurring chemical compound from animals, bacteria, and plants. It has skin-softening, protecting, soothing, and wound-healing properties. Some cosmetic manufacturers produce allantoin synthetically. All procedures were approved by the medical ethics committee of Jinjiang People’s Hospital (no. 2015-02-003). 3.1. Drugs and MaterialsWard SR, Satle RJ: Topical Agents in Burn and Wound Care. Pharmacology Series Physical Therapy. 1995, 75 (6): 526-538. Rosehip oil has many uses in the cosmetic industry. It may help to protect and hydrate the skin, fight free radical damage, reduce wrinkles, restore elasticity, correct dark spots and reduce the appearance of scars. The wound healing after one month of treatment and the evaluation standard of curative effect refer to the therapeutic effect standard of Guiding Principles for Clinical Research of Chinese New Drugs in the Treatment of Acute Sores formulated and issued by the Ministry of Health [ 10]. (1) Cure: local swelling disappeared, skin color returned to normal, and the ulcer surface completely healed; (2) markedly effect: local swelling and skin color improved, wound secretion decreased significantly, most of necrotic tissues liquefied and separated, granulation tissue growth was obvious, and the ulcer surface reduced by more than 70%; (3) effective: local swelling and skin color improved, wound secretion decreased, necrotic tissue partially liquefied and separated, the granulation tissue grew, and the ulcer surface reduced by 30%∼70%; (4) no effect: local swelling and skin color did not improve, wound secretion did not significantly reduce, granulation tissue growth was not obvious, and the ulcer surface did not change or expand. The effective rate = (cured + markedly effective + effective)/total number × 100%. 3.3. Statistical Methods High temperatures or excessive handling may alter the consistency of the ointment. This will not change its effectiveness. Dréno B, et al. (2018). Prevention and reduction of atrophic acne scars with adapalene 0.3%/benzoyl peroxide 2.5% gel in subjects with moderate or severe facial acne: Results of a 6-month randomized, vehicle-controlled trial using intra-individual comparison.